- The Morning Dose
- Posts
- The Morning Dose #100: SARMs for Fat Loss, Nootropics, and ACE-031
The Morning Dose #100: SARMs for Fat Loss, Nootropics, and ACE-031
The ONLY Underground Biohacking Newsletter

Welcome to The Morning Dose, your one-stop shop for all things peptides, TRT, fitness, anti-aging, and everything in between.
Pour your morning coffee and lock in for this week’s groundbreaking news and rearch from the world of science-based biohacking, TRT, peptides and anti-aging.
In this week’s edition of The Morning Dose:
🍓Cutting-Edge SARMs for Fat Loss in 2025
🌙 Sleep-Smart: Top Nootropic Breakthroughs for Better Rest in 2025
💪 ACE-031: Muscle Growth Research Advancements in 2025
☕️ First time reading? I’m James, and this is The Morning Dose. Every week, our team scours hundreds of sources to bring you need-to-know news and insights you won’t find elsewhere. All in 5 minutes.
Did someone forward you this email? Sign up here.
🍓Cutting-Edge SARMs for Fat Loss in 2025
Weight gain for women isn’t just about eating more—it involves smart supplementation, hormone balance, and support for muscle growth. In 2025, targeted weight gain formulas are gaining traction in both wellness and physique-enhancement communities.
What’s Covered:
🍓 Mechanisms of Action
These supplements focus on increasing caloric intake, supporting nutrient absorption, and optimizing anabolic hormone activity. Key compounds may influence appetite signalling, insulin response, and lean muscle development.
🍓 Best Supplements for Results
Leading formulas include mass gainers, creatine, appetite stimulants, and adaptogens. Each offers unique support—from calorie-dense blends to muscle-cell hydration and reduced stress hormone interference.
🍓 Usage & Outcomes
Protocols vary by metabolism, activity level, and goals. Research-backed approaches recommend pairing these supplements with resistance training and balanced macronutrient intake for effective and sustainable weight gain.
Want to explore the top-rated weight gain supplements for women in 2025?
👉 Click here to read the full guide on Muscle and Brawn
🌙 Sleep-Smart: Top Nootropic Breakthroughs for Better Rest in 2025
Nootropics are increasingly studied for their impact on sleep quality, circadian rhythm support, and overnight cognitive recovery. In 2025, research continues to explore how specific compounds can promote restful sleep without sedative drawbacks.
What’s Covered:
🌙 Mechanisms of Action
Sleep-supportive nootropics work through various pathways—some modulate GABAergic signalling, others support melatonin synthesis, reduce cortisol, or enhance REM cycles. The goal is to induce natural, non-disruptive sleep while supporting neurological restoration.
🌙 Top Compounds for Sleep
Leading nootropics include L-Theanine, Magnesium L-Threonate, Apigenin, and Glycine. Each shows distinct benefits in sleep latency, depth, and morning alertness. Some are combined for synergistic effects in calming pre-sleep brain activity.
🌙 Supplementation & Sleep Cycles
Studies evaluate dose timing, frequency, and combination with lifestyle practices such as blue light blocking and relaxation protocols. Nootropics may support better sleep architecture without typical grogginess associated with sleep aids.
Curious which nootropics may best support sleep in 2025?
👉 Click here to read the full guide on Muscle and Brawn
💪 ACE-031: Muscle Growth Research Advancements in 2025
ACE-031 is a synthetic research peptide studied for its potential to inhibit myostatin, a protein that regulates muscle growth. In 2025, ongoing investigations continue to assess its role in muscle development, strength retention, and degenerative muscle conditions.
💪 Mechanisms of Action
ACE-031 acts as a decoy receptor for myostatin, preventing it from binding to natural receptors. This interference may lead to increased muscle mass by lifting growth suppression pathways. Researchers also examine its impact on bone density and lean tissue support.
💪 Potential Applications in Muscle Research
Current research explores ACE-031 in the context of muscle-wasting disorders, post-injury recovery, and athletic performance models. Its ability to promote lean mass without direct anabolic action is of particular interest in long-term studies.
💪 Study Designs & Safety
Investigations monitor variables such as dosing intervals, duration of exposure, and response in both animal and controlled lab environments. Side effect profiles and off-target interactions remain key areas of interest for researchers.
Curious how ACE-031 is shaping muscle research in 2025?
👉 Click here to read the full guide on Muscle and Brawn
-The Morning Dose
What did you think of today's edition? |
PS - Have questions or suggestions? Hit reply and let us know what you think.
Disclaimer: This content is NOT medical advice. The information included in these emails is intended for entertainment and informational purposes only.