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- The Morning Dose #103: N-Acetyl Epitalon Amidate, Nootropics for Brain Fog, Joe Rogan’s supplement stack
The Morning Dose #103: N-Acetyl Epitalon Amidate, Nootropics for Brain Fog, Joe Rogan’s supplement stack
The ONLY Underground Biohacking Newsletter

Welcome to The Morning Dose, your one-stop shop for all things peptides, TRT, fitness, anti-aging, and everything in between.
Pour your morning coffee and lock in for this week’s groundbreaking news and rearch from the world of science-based biohacking, TRT, peptides and anti-aging.
In this week’s edition of The Morning Dose:
🧬 Longevity Insights: N-Acetyl Epitalon Amidate’s Emerging Role in 2025
🧠 Clearer Minds Ahead: Top Nootropics for Brain Fog Relief in 2025
💊 Joe Rogan’s Supplement Picks Fueling 2025 Biohacking
☕️ First time reading? I’m James, and this is The Morning Dose. Every week, our team scours hundreds of sources to bring you need-to-know news and insights you won’t find elsewhere. All in 5 minutes.
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🧬 Longevity Insights: N-Acetyl Epitalon Amidate’s Emerging Role in 2025
N-Acetyl Epitalon Amidate is a next-gen derivative of the original Epitalon peptide, studied for its potential to regulate biological aging through telomerase activation and pineal gland support. In 2025, research expands into its enhanced stability and bioavailability in experimental models.
What’s Covered:
🧬 Mechanisms of Action
This modified peptide is investigated for its ability to stimulate telomerase, regulate circadian rhythms via melatonin, and support DNA repair processes. The acetylation and amidation may improve absorption and peptide resistance to degradation.
🧬 Research Focus & Benefits
Studies have explored its potential in lifespan extension, cellular regeneration, and anti-aging pathways. Preclinical data suggest benefits in mitochondrial function, oxidative stress reduction, and pineal gland signalling.
🧬 Stability & Dosing
Compared to Epitalon, the N-acetyl amidate form is studied for improved peptide half-life and targeted action. Dosage protocols in lab settings aim to optimize frequency without desensitization.
Curious how N-Acetyl Epitalon Amidate is advancing longevity research in 2025?
👉 Click here to read the full guide on Muscle and Brawn
🧠 Clearer Minds Ahead: Top Nootropics for Brain Fog Relief in 2025
Brain fog remains a leading concern in cognitive health studies, especially in post-viral recovery, sleep-deprived individuals, and high-performance environments. In 2025, nootropic research continues to focus on mental clarity, focus, and neuroinflammation.
What’s Covered:
🧠 Mechanisms of Action
Nootropics for brain fog often target cholinergic transmission, dopamine modulation, and neuroinflammation. Some also support mitochondrial energy production and synaptic plasticity to improve executive function.
🧠 Key Compounds Studied
Top nootropics include Citicoline, Rhodiola Rosea, L-Tyrosine, Lion’s Mane, and Acetyl-L-Carnitine. Each compound is examined for memory, stress resilience, and focus under fatigue or cognitive load.
🧠 Stacking & Usage Patterns
Formulas often combine adaptogens, amino acids, and cognitive enhancers. Research suggests rotating compounds or cycling to avoid tolerance and enhance long-term effects.
Curious which nootropics help cut through brain fog in 2025?
👉 Click here to read the full guide on Muscle and Brawn
💊 Joe Rogan’s Supplement Picks Fueling 2025 Biohacking
Joe Rogan’s supplement stack continues to spark interest in performance, brain health, and biohacking circles. In 2025, many compounds from his routine are studied for their synergy in cognitive enhancement, recovery, and cellular support.
What’s Covered:
💊 Mechanisms of Action
These supplements range from mitochondrial support and nootropic enhancement to hormone and immune optimization. Key pathways include inflammation control, neurotransmission, and cellular repair.
💊 Notable Compounds in His Stack
Among the most talked-about: Alpha Brain, NMN, Vitamin D3, Krill Oil, Creatine, and Lion’s Mane. Each one is reviewed for both personal anecdotal use and emerging scientific backing.
💊 Research & Application
Many are taken daily or cycled based on training demands, mental workload, or immune needs. Studies support combining adaptogens with micronutrients and cognitive boosters for optimal output.
Curious what’s in Joe Rogan’s research-backed supplement stack in 2025?
👉 Click here to read the full guide on Muscle and Brawn
-The Morning Dose
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Disclaimer: This content is NOT medical advice. The information included in these emails is intended for entertainment and informational purposes only.